Welcome to PyOPERA’s documentation!#
PyOPERA (/py’opera/) is a Python wrapper around the library generated by OPERA and offers a simple and intuitive API.
The OPERA app was developed by the NIH to run Quantitative structure–activity/property relationship (QSAR/QSPR) models. QSAR models provide a way to predict chemical toxicology without the need of animal models (Madden et al., 2020). The NIH project spun off a repo of OPERA models using MATLAB, this project uses the output of the NIH OPERA open-source project and converts it to a full Python package that is as usable as possible by Python developers.